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P0301

Engine Misfire P0301 Cylinder 1 2017 Toyota Prius Prime (Phev)

By ClearTheCode · Published 2026-05-25 · ~4 min read

Experiencing an engine misfire on cylinder 1 in your 2017 Toyota Prius Prime (Phev) with a P0301 code? Discover common causes and practical diagnostic steps to resolve the issue.

At a glance P0301

Difficulty
6/10 — Intermediate diagnostics
Est. repair cost
$120 – $450 (parts + typical shop labor)

Diagnostic workflow

  1. Confirm P0301 with a live scan — note pending vs stored and freeze frame data.
  2. Inspect wiring/connectors and related sensors before replacing modules.
  3. Clear codes and road-test; re-scan after two drive cycles if the monitor must set.

If your 2017 Toyota Prius Prime (Phev) has suddenly started running rough, lost power, or the check engine light has illuminated, you might be dealing with an engine misfire on cylinder 1, often indicated by a P0301 diagnostic trouble code. This specific issue means the engine's computer has detected that cylinder 1 is not contributing its fair share of power to the engine's rotation. Addressing this promptly is crucial for maintaining your hybrid's performance and fuel efficiency, as a persistent misfire can lead to further engine damage or catalytic converter issues.

What drivers notice on this 2017 Toyota Prius Prime (Phev)

When cylinder 1 misfires, the driving experience in your Prius Prime can change noticeably. You might feel a distinct shudder or vibration, especially at idle or low speeds, as the engine struggles to run smoothly with one cylinder not firing correctly. The vehicle's acceleration may feel sluggish, and you might notice a decrease in overall power. Given the Prius Prime's hybrid nature, the gasoline engine's engagement might become more pronounced or erratic, as the system tries to compensate for the misfire, potentially running the engine more often than usual to maintain charge or propulsion. This can lead to a less refined driving experience and a noticeable drop in the efficiency you expect from your plug-in hybrid.

At a glance: difficulty, repair cost, and diagnostic workflow

  • Difficulty Rating: 6/10 — 6/10 — Intermediate diagnostics
  • Common Symptoms: Check Engine Light (CEL) illuminated: This is often the most obvious sign, and a scan tool will likely reveal the P0301 ; Rough idle or vibrations: The engine may shake or vibrate more than usual, particularly when stationary or at low RPMs, ; Reduced power and acceleration: The vehicle might feel sluggish, struggle to accelerate, or have difficulty maintaining ; Decreased fuel economy: A misfiring cylinder wastes fuel because unburnt fuel can be expelled through the exhaust, leadi
  • Estimated Repair Cost: $120–$450 (parts + typical shop labor)
  • OEM Tooling Required: Standard OBD-II scanner and hand tools

Diagnostic workflow:

  1. Confirm P0301 with a live scan — note pending vs stored and freeze frame data.
  2. Inspect wiring/connectors and related sensors before replacing modules.
  3. Clear codes and road-test; re-scan after two drive cycles if the monitor must set.

See the P0301 code reference and topic hub for related guides.

Symptoms and warning signs of Engine Misfire P0301 Cylinder 1

Recognizing the symptoms of an engine misfire P0301 Cylinder 1 is the first step towards diagnosis. For your 2017 Toyota Prius Prime, these can include:

  • Check Engine Light (CEL) illuminated: This is often the most obvious sign, and a scan tool will likely reveal the P0301 code, specifically pointing to cylinder 1. The light may flash, indicating a severe misfire that could damage the catalytic converter.
  • Rough idle or vibrations: The engine may shake or vibrate more than usual, particularly when stationary or at low RPMs, as the engine tries to compensate for the missing power stroke from cylinder 1.
  • Reduced power and acceleration: The vehicle might feel sluggish, struggle to accelerate, or have difficulty maintaining speed on inclines, directly impacting your driving confidence.
  • Decreased fuel economy: A misfiring cylinder wastes fuel because unburnt fuel can be expelled through the exhaust, leading to a noticeable drop in MPG and increased emissions.
  • Hesitation or stumbling: The engine might momentarily lose power or

This guide is not a substitute for OEM service procedures; use a qualified technician for safety-critical repairs.

Frequently asked questions

How urgent is this problem?

If symptoms are worsening or safety systems are affected, diagnose soon; minor issues can often wait for a scheduled service visit.

Can I drive with this issue?

Short trips may be acceptable for some faults, but stop driving if you notice overheating, loss of braking, steering problems, or strong fuel smells.

Do I need a dealer scan tool?

A basic OBD-II scanner helps confirm codes; some steps still need visual checks and meter tests described above.

Helpful links

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